Pure Water: The Unsung Hero Of The Lab

 Pure water plays a pivotal role in almost every life science experiment, diagnostic test or chemical reaction. It’s so important, there’s even a high impact journal dedicated to reporting on new water-based research and purification methods. Sadly, lab water still rarely gets the attention it deserves.


The Ultimate Dissolution Solution

Without pure water, very few experiments, tests or reactions would be possible. Thanks to its favorable chemical and physical properties, water is often considered the ‘universal solvent’ as it dissolves more substances than any other liquid. Perhaps even more importantly, many biochemical reactions will only take place within aqueous solutions.



Some of the most interesting science being carried out at the moment pushes the boundaries of analytical sensitivity. Techniques such as inductively-coupled plasma mass spectrometry (ICP-MS), thermal ionization mass spectrometry (TIMS) and ICP atomic emission spectrometry (ICP-AES) allow researchers to explore biological and chemical systems in more detail and at greater resolution than ever before, including being able to detect the presence of chemicals and factors at trace (<100 ppm) and ultra-trace (<1 ppm) concentrations.

As an example, such sensitivity allows us to detect low expression biomarkers so that we can better diagnose and treat patients, helping to turn the promise of personalized medicine into a reality. High sensitivity analysis is also highly useful when working with environmental samples, so that researchers can better track global climate and environmental change.

Daily Experiments are the Simple, but Essential, Steps Behind Major Discoveries

Baby steps in science are made through daily experiments that produce consistent, reliable results. They are the building blocks that lay the foundations for great scientific breakthroughs. As such, a large part of your time and focus in the lab is spent on getting these experiments functioning effectively.

For example, when Andrew Z. Fire and Craig C. Mello were working to understand the mechanism of RNA interference (research for which they shared the Nobel Prize in Physiology or Medicine in 2006) the day-to-day activities of their studies would have involved cloning, RNA synthesis and dsRNA injection to name but a few. It was their dedication and perseverance, diligently and accurately repeating all of these steps while carefully altering one variable at a time that ultimately led to the development of one of biology’s most powerful techniques. I expect that similar daily grind was behind the successful cloning of GFP from jellyfish, which is now the biologist’s favorite fluorescent marker protein.

Accurate Diagnostic Tests Save Lives

Alkaline phosphatase is an enzyme present inside all body cells – tests to assay its function are used to diagnose bone, liver, gallbladder, parathyroid gland and bile duct disease, as well as Vitamin D deficiency. However, the results of these tests are negatively influenced by fluoride, phosphate, zinc, manganese, arsenate, EDTA, bacteria and/or endotoxins present in the sample and/or reagents being used.
Iron analysis is used to investigate a wide range of problems, from depression, joint pain and irregular heartbeat to liver trouble, diabetes and infertility. However, the reliability of iron quantification in blood samples is reduced by the presence of EDTA, oxalate and fluoride.

Using High Quality Reagents Saves you Time and Money

  • ncrease experimental reproducibility
  • Ensure optimal enzyme activity
  • Prevent premature aging of your equipment
  • Save you from having to re-prepare your buffers over and over again (they will last longer if they are free of microorganisms and organic material)
  • In short – save you time and money!

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